Helicases at Work: The Importance of Nucleic Acids Unwinding Under Cold Stress

Helicases at Work: The Importance of Nucleic Acids Unwinding Under Cold Stress

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Separation of duplex strands of nucleic acids is a vital process in the nucleic acid metabolism and survival of all living organisms.Helicases are defined as enzymes that are intended to unwind the double-stranded nucleic acids.Helicases play a prominent role in the cold adaptation of plants and bacteria.Cold Birthday Train stress can increase double-strand DNA breaks, generate reactive oxygen species, cause DNA methylation, and stabilize the secondary structure of RNA molecules.In this review, Bike Parts - Tires - 29-700 we discuss how helicases play important roles in adaptive responses to cellular stress caused by low temperature conditions, particularly in bacteria and plants.

We also provide a glimpse of the eminence of helicase function over nuclease when an enzyme has both helicase and nuclease functions.